Screening of Pleural Mesothelioma Cell Lines for Kinase Activity May Identify New Mechanisms of Therapy Resistance in Patients Receiving Platin-Based Chemotherapy

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumor associated with a dismal prognosis. Multimodal therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons underlying the rather poor effi...

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Udgivet i:J Oncol
Main Authors: Borchert, Sabrina, Suckrau, Pia-Maria, Wessolly, Michael, Mairinger, Elena, Hegedus, Balazs, Hager, Thomas, Herold, Thomas, Eberhardt, Wildfried E. E., Wohlschlaeger, Jeremias, Aigner, Clemens, Bankfalvi, Agnes, Schmid, Kurt Werner, Walter, Robert F. H., Mairinger, Fabian D.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942867/
https://ncbi.nlm.nih.gov/pubmed/31929796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2902985
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