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Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1

Purkinje neuron dendritic degeneration precedes cell loss in cerebellar ataxia, but the basis for dendritic vulnerability in ataxia remains poorly understood. Recent work has suggested that potassium (K(+)) channel dysfunction and consequent spiking abnormalities contribute to Purkinje neuron degene...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Chopra, Ravi, Bushart, David D., Shakkottai, Vikram G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976172/
https://ncbi.nlm.nih.gov/pubmed/29847609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198040
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