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Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1
Purkinje neuron dendritic degeneration precedes cell loss in cerebellar ataxia, but the basis for dendritic vulnerability in ataxia remains poorly understood. Recent work has suggested that potassium (K(+)) channel dysfunction and consequent spiking abnormalities contribute to Purkinje neuron degene...
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| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5976172/ https://ncbi.nlm.nih.gov/pubmed/29847609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198040 |
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