Kynurenine pathway is altered in patients with SLE and associated with severe fatigue

OBJECTIVE: Fatigue has been reported as the most disturbing symptom in a majority of patients with SLE. Depression is common and often severe. Together these symptoms cause significant morbidity and affect patients with otherwise relatively mild disease. Tryptophan and its metabolites in the kynuren...

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Detalhes bibliográficos
Publicado no:Lupus Sci Med
Main Authors: Åkesson, Karolina, Pettersson, Susanne, Ståhl, Sara, Surowiec, Izabella, Hedenström, Mattias, Eketjäll, Susanna, Trygg, Johan, Jakobsson, Per-Johan, Gunnarsson, Iva, Svenungsson, Elisabet, Idborg, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://ncbi.nlm.nih.gov/pubmed/29868176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2017-000254
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