Kynurenine pathway is altered in patients with SLE and associated with severe fatigue

OBJECTIVE: Fatigue has been reported as the most disturbing symptom in a majority of patients with SLE. Depression is common and often severe. Together these symptoms cause significant morbidity and affect patients with otherwise relatively mild disease. Tryptophan and its metabolites in the kynuren...

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Detaylı Bibliyografya
Yayımlandı:Lupus Sci Med
Asıl Yazarlar: Åkesson, Karolina, Pettersson, Susanne, Ståhl, Sara, Surowiec, Izabella, Hedenström, Mattias, Eketjäll, Susanna, Trygg, Johan, Jakobsson, Per-Johan, Gunnarsson, Iva, Svenungsson, Elisabet, Idborg, Helena
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2018
Konular:
Immunology and Inflammation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://ncbi.nlm.nih.gov/pubmed/29868176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2017-000254
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