Kynurenine pathway is altered in patients with SLE and associated with severe fatigue

OBJECTIVE: Fatigue has been reported as the most disturbing symptom in a majority of patients with SLE. Depression is common and often severe. Together these symptoms cause significant morbidity and affect patients with otherwise relatively mild disease. Tryptophan and its metabolites in the kynuren...

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Vydáno v:Lupus Sci Med
Hlavní autoři: Åkesson, Karolina, Pettersson, Susanne, Ståhl, Sara, Surowiec, Izabella, Hedenström, Mattias, Eketjäll, Susanna, Trygg, Johan, Jakobsson, Per-Johan, Gunnarsson, Iva, Svenungsson, Elisabet, Idborg, Helena
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2018
Témata:
Immunology and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://ncbi.nlm.nih.gov/pubmed/29868176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2017-000254
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