Kynurenine pathway is altered in patients with SLE and associated with severe fatigue

OBJECTIVE: Fatigue has been reported as the most disturbing symptom in a majority of patients with SLE. Depression is common and often severe. Together these symptoms cause significant morbidity and affect patients with otherwise relatively mild disease. Tryptophan and its metabolites in the kynuren...

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Dettagli Bibliografici
Pubblicato in:Lupus Sci Med
Autori principali: Åkesson, Karolina, Pettersson, Susanne, Ståhl, Sara, Surowiec, Izabella, Hedenström, Mattias, Eketjäll, Susanna, Trygg, Johan, Jakobsson, Per-Johan, Gunnarsson, Iva, Svenungsson, Elisabet, Idborg, Helena
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2018
Soggetti:
Immunology and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://ncbi.nlm.nih.gov/pubmed/29868176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2017-000254
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