Kynurenine pathway is altered in patients with SLE and associated with severe fatigue

OBJECTIVE: Fatigue has been reported as the most disturbing symptom in a majority of patients with SLE. Depression is common and often severe. Together these symptoms cause significant morbidity and affect patients with otherwise relatively mild disease. Tryptophan and its metabolites in the kynuren...

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Dades bibliogràfiques
Publicat a:Lupus Sci Med
Autors principals: Åkesson, Karolina, Pettersson, Susanne, Ståhl, Sara, Surowiec, Izabella, Hedenström, Mattias, Eketjäll, Susanna, Trygg, Johan, Jakobsson, Per-Johan, Gunnarsson, Iva, Svenungsson, Elisabet, Idborg, Helena
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2018
Matèries:
Immunology and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976103/
https://ncbi.nlm.nih.gov/pubmed/29868176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/lupus-2017-000254
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