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Higher-order structural interrogation of antibodies using middle-down hydrogen/deuterium exchange mass spectrometry

Although X-ray crystallography is the “gold standard” method for protein higher-order structure analysis, the challenges of antibody crystallization and the time-consuming data analysis involved make this technique unsuitable for routine structural studies of antibodies. In addition, crystallography...

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Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Pan, Jingxi, Zhang, Suping, Chou, Albert, Borchers, Christoph H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975933/
https://ncbi.nlm.nih.gov/pubmed/29910905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03420e
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