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Therapy development in Huntington disease: From current strategies to emerging opportunities
Huntington disease (HD) is a progressive autosomal dominant neurodegenerative disorder in which patients typically present with uncontrolled involuntary movements and subsequent cognitive decline. In 1993, a CAG trinucleotide repeat expansion in the coding region of the huntingtin (HTT) gene was ide...
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| Pubblicato in: | Am J Med Genet A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5975251/ https://ncbi.nlm.nih.gov/pubmed/29218782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.38494 |
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