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TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities
Two decades ago, the recognition of protein misfolding and aggregate accumulation as defining features of neurodegenerative disease set the stage for a thorough examination of how protein quality control is maintained in neurons and in other nonneuronal cells in the central nervous system (CNS). Aut...
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| Veröffentlicht in: | Neurobiol Dis |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291370/ https://ncbi.nlm.nih.gov/pubmed/29852219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.05.012 |
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