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PGC-1α at the intersection of bioenergetics regulation and neuron function: From Huntington’s disease to Parkinson’s disease and beyond
Neurons are specialized cells with unique features, including a constant high demand for energy. Mitochondria satisfy this constant demand, and are emerging as a central target for dysfunction in neurodegenerative disorders, such as Huntington’s disease (HD) and Parkinson’s disease. PPARγ co-activat...
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Main Authors: | , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3506171/ https://ncbi.nlm.nih.gov/pubmed/22100502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2011.10.004 |
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