Conformational Stability of the Hemagglutinin of H5N1 Influenza A Viruses Influences Susceptibility to Broadly Neutralizing Stem Antibodies

Vaccines that elicit broadly neutralizing antibodies to the conserved stem of hemagglutinin (HA) are being developed as universal influenza vaccines that protect against influenza across multiple years. However, different influenza virus strains, even those in the same subtype with identical stem se...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Wang, Wei, Song, Hyo Sook, Keller, Paul W., Alvarado-Facundo, Esmeralda, Vassell, Russell, Weiss, Carol D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974491/
https://ncbi.nlm.nih.gov/pubmed/29593038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00247-18
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