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Intermonomer Interactions in Hemagglutinin Subunits HA1 and HA2 Affecting Hemagglutinin Stability and Influenza Virus Infectivity

Influenza virus hemagglutinin (HA) mediates virus entry by binding to cell surface receptors and fusing the viral and endosomal membranes following uptake by endocytosis. The acidic environment of endosomes triggers a large-scale conformational change in the transmembrane subunit of HA (HA2) involvi...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Wang, Wei, DeFeo, Christopher J., Alvarado-Facundo, Esmeralda, Vassell, Russell, Weiss, Carol D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580181/
https://ncbi.nlm.nih.gov/pubmed/26269180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00939-15
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