Intermonomer Interactions in Hemagglutinin Subunits HA1 and HA2 Affecting Hemagglutinin Stability and Influenza Virus Infectivity

Influenza virus hemagglutinin (HA) mediates virus entry by binding to cell surface receptors and fusing the viral and endosomal membranes following uptake by endocytosis. The acidic environment of endosomes triggers a large-scale conformational change in the transmembrane subunit of HA (HA2) involvi...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Wang, Wei, DeFeo, Christopher J., Alvarado-Facundo, Esmeralda, Vassell, Russell, Weiss, Carol D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580181/
https://ncbi.nlm.nih.gov/pubmed/26269180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00939-15
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