Glycosylation of Residue 141 of Subtype H7 Influenza A Hemagglutinin (HA) Affects HA-Pseudovirus Infectivity and Sensitivity to Site A Neutralizing Antibodies

Human infections with H7 subtype influenza virus have been reported, including an H7N7 outbreak in Netherlands in 2003 and H7N9 infections in China in 2013. Previously, we reported murine monoclonal antibodies (mAbs) that recognize the antigenic site A of H7 hemagglutinin (HA). To better understand...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Alvarado-Facundo, Esmeralda, Vassell, Russell, Schmeisser, Falko, Weir, Jerry P., Weiss, Carol D., Wang, Wei
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749315/
https://ncbi.nlm.nih.gov/pubmed/26862918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149149
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