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Influenza Virus M2 Protein Ion Channel Activity Helps To Maintain Pandemic 2009 H1N1 Virus Hemagglutinin Fusion Competence during Transport to the Cell Surface

The influenza virus hemagglutinin (HA) envelope protein mediates virus entry by first binding to cell surface receptors and then fusing viral and endosomal membranes during endocytosis. Cleavage of the HA precursor (HA0) into a surface receptor-binding subunit (HA1) and a fusion-inducing transmembra...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Alvarado-Facundo, Esmeralda, Gao, Yamei, Ribas-Aparicio, Rosa María, Jiménez-Alberto, Alicia, Weiss, Carol D., Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338904/
https://ncbi.nlm.nih.gov/pubmed/25473053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03253-14
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