Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in developed countries. An in vitro NAFLD model would permit mechanistic studies and enable high-throughput therapeutic screening. While hepatic cancer-derived cell lines are a convenient, renewable resource, their g...

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Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Lyall, Marcus J., Cartier, Jessy, Thomson, John P., Cameron, Kate, Meseguer-Ripolles, Jose, O'Duibhir, Eoghan, Szkolnicka, Dagmara, Villarin, Baltasar Lucendo, Wang, Yu, Blanco, Giovanny Rodriguez, Dunn, Warwick B., Meehan, Richard R., Hay, David C., Drake, Amanda J.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2018
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974453/
https://ncbi.nlm.nih.gov/pubmed/29786565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0362
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