Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation

מאת Lyall, Marcus J., Thomson, John P., Cartier, Jessy, Ottaviano, Raffaele, Kendall, Timothy J., Meehan, Richard R., Drake, Amanda J.
הוצא לאור ב Epigenetics (2019)

Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD

מאת Lyall, Marcus J., Cartier, Jessy, Richards, James A, Cobice, Diego, Thomson, John P, Meehan, Richard R, Anderton, Stephen M, Drake, Amanda J
הוצא לאור ב Wellcome Open Res (2017)

Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes

מאת Cameron, Kate, Tan, Rosanne, Schmidt-Heck, Wolfgang, Campos, Gisela, Lyall, Marcus J., Wang, Yu, Lucendo-Villarin, Baltasar, Szkolnicka, Dagmara, Bates, Nicola, Kimber, Susan J., Hengstler, Jan G., Godoy, Patricio, Forbes, Stuart J., Hay, David C.
הוצא לאור ב Stem Cell Reports (2015)

Loss of Tet1 associated 5-hydroxymethylcytosine is concomitant with aberrant promoter hypermethylation in liver cancer

מאת Thomson, John P, Ottaviano, Raffaele, Unterberger, Elif, Lempiäinen, Harri, Muller, Arne, Terranova, Remi, Illingworth, Robert S., Webb, Shaun, Kerr, Alastair R. W., Lyall, Marcus J, Drake, Amanda J, Wolf, C Roland, Moggs, Jonathan G, Schwarz, Michael, Meehan, Richard R
הוצא לאור ב Cancer Res (2016)

Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

מאת Lyall, Marcus J., Cartier, Jessy, Thomson, John P., Cameron, Kate, Meseguer-Ripolles, Jose, O'Duibhir, Eoghan, Szkolnicka, Dagmara, Villarin, Baltasar Lucendo, Wang, Yu, Blanco, Giovanny Rodriguez, Dunn, Warwick B., Meehan, Richard R., Hay, David C., Drake, Amanda J.
הוצא לאור ב Philos Trans R Soc Lond B Biol Sci (2018)

A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis

מאת Sinton, Matthew C., Meseguer-Ripolles, Jose, Lucendo-Villarin, Baltasar, Wernig-Zorc, Sara, Thomson, John P., Carter, Roderick N., Lyall, Marcus J., Walker, Paul D., Thakker, Alpesh, Meehan, Richard R., Lavery, Gareth G., Morton, Nicholas M., Ludwig, Christian, Tennant, Daniel A., Hay, David C., Drake, Amanda J.
הוצא לאור ב iScience (2020)