Modulating Innate Immunity Improves Hepatitis C Virus Infection and Replication in Stem Cell-Derived Hepatocytes

In this study, human embryonic stem cell-derived hepatocytes (hESC-Heps) were investigated for their ability to support hepatitis C virus (HCV) infection and replication. hESC-Heps were capable of supporting the full viral life cycle, including the release of infectious virions. Although supportive,...

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Main Authors: Zhou, Xiaoling, Sun, Pingnan, Lucendo-Villarin, Baltasar, Angus, Allan G.N., Szkolnicka, Dagmara, Cameron, Kate, Farnworth, Sarah L., Patel, Arvind H., Hay, David C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110790/
https://ncbi.nlm.nih.gov/pubmed/25068132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.04.018
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