Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

Mounting an effective immune response against cancer requires the activation of innate and adaptive immune cells. Metastatic melanoma is the most aggressive form of skin cancer. While immunotherapies have shown a remarkable success in melanoma treatment, patients develop resistance by mechanisms tha...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Figueiredo, Carlos R., Azevedo, Ricardo A., Mousdell, Sasha, Resende-Lara, Pedro T., Ireland, Lucy, Santos, Almudena, Girola, Natalia, Cunha, Rodrigo L. O. R., Schmid, Michael C., Polonelli, Luciano, Travassos, Luiz R., Mielgo, Ainhoa
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974174/
https://ncbi.nlm.nih.gov/pubmed/29875777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01132
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