Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

Mounting an effective immune response against cancer requires the activation of innate and adaptive immune cells. Metastatic melanoma is the most aggressive form of skin cancer. While immunotherapies have shown a remarkable success in melanoma treatment, patients develop resistance by mechanisms tha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Figueiredo, Carlos R., Azevedo, Ricardo A., Mousdell, Sasha, Resende-Lara, Pedro T., Ireland, Lucy, Santos, Almudena, Girola, Natalia, Cunha, Rodrigo L. O. R., Schmid, Michael C., Polonelli, Luciano, Travassos, Luiz R., Mielgo, Ainhoa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974174/
https://ncbi.nlm.nih.gov/pubmed/29875777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01132
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