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Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis

Pancreatic ductal adenocarcinoma (PDA) is one of the deadliest cancers due to its aggressive and metastatic nature. PDA is characterized by a rich tumor stroma with abundant macrophages, fibroblasts, and collagen deposition that can represent up to 90% of the tumor mass. Activation of the tyrosine k...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Ireland, Lucy, Luckett, Teifion, Schmid, Michael C., Mielgo, Ainhoa
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056881/
https://ncbi.nlm.nih.gov/pubmed/32174917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00297
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