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Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis

Pancreatic ductal adenocarcinoma (PDA) is one of the deadliest cancers due to its aggressive and metastatic nature. PDA is characterized by a rich tumor stroma with abundant macrophages, fibroblasts, and collagen deposition that can represent up to 90% of the tumor mass. Activation of the tyrosine k...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Ireland, Lucy, Luckett, Teifion, Schmid, Michael C., Mielgo, Ainhoa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056881/
https://ncbi.nlm.nih.gov/pubmed/32174917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00297
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