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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
Microtubule-targeting agents (MTAs) like taxol and vinblastine are among the most successful chemotherapeutic drugs against cancer. Here, we describe a fluorescence anisotropy-based assay that specifically probes for ligands targeting the recently discovered maytansine site of tubulin. Using this as...
में बचाया:
| में प्रकाशित: | Nat Commun |
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| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5974090/ https://ncbi.nlm.nih.gov/pubmed/29844393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04535-8 |
| टैग : |
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