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Structural basis of tubulin tyrosination by tubulin tyrosine ligase
Tubulin tyrosine ligase (TTL) catalyzes the post-translational retyrosination of detyrosinated α-tubulin. Despite the indispensable role of TTL in cell and organism development, its molecular mechanism of action is poorly understood. By solving crystal structures of TTL in complex with tubulin, we h...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563685/ https://ncbi.nlm.nih.gov/pubmed/23358242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201211017 |
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