Electron cryo-microscopy structure of Ebola nucleoprotein reveals a mechanism for nucleocapsid-like assembly

Ebola virus nucleoprotein (eNP) assembles into higher-ordered structures that form the viral nucleocapsid (NC) and serve as the scaffold for viral RNA synthesis. However, molecular insights into the NC assembly process are lacking. Using a hybrid approach, we characterized the NC-like assembly of eN...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Su, Zhaoming, Wu, Chao, Shi, Liuqing, Luthra, Priya, Pintilie, Grigore D., Johnson, Britney, Porter, Justin R., Ge, Peng, Chen, Muyuan, Liu, Gai, Frederick, Thomas E., Binning, Jennifer M., Bowman, Gregory R., Zhou, Z. Hong, Basler, Christopher F., Gross, Michael L., Leung, Daisy W., Chiu, Wah, Amarasinghe, Gaya K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973842/
https://ncbi.nlm.nih.gov/pubmed/29474922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.009
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