Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions

To fulfill bioenergetic demands of activation, T cells perform aerobic glycolysis, a process common to highly proliferative cells in which glucose is fermented into lactate rather than oxidized in mitochondria. However, the signaling events that initiate aerobic glycolysis in T cells remain unclear....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Menk, Ashley V., Scharping, Nicole E., Moreci, Rebecca S., Zeng, Xue, Guy, Cliff, Salvatore, Sonia, Bae, Heekyong, Xie, Jianxin, Young, Howard A., Wendell, Stacy Gelhaus, Delgoffe, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973810/
https://ncbi.nlm.nih.gov/pubmed/29425506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.040
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados