Lipodystrophic syndromes due to LMNA mutations: recent developments on biomolecular aspects, pathophysiological hypotheses and therapeutic perspectives

Mutations in LMNA, encoding A-type lamins, are responsible for laminopathies including muscular dystrophies, lipodystrophies, and premature ageing syndromes. LMNA mutations have been shown to alter nuclear structure and stiffness, binding to partners at the nuclear envelope or within the nucleoplasm...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Vigouroux, Corinne, Guénantin, Anne-Claire, Vatier, Camille, Capel, Emilie, Le Dour, Caroline, Afonso, Pauline, Bidault, Guillaume, Béréziat, Véronique, Lascols, Olivier, Capeau, Jacqueline, Briand, Nolwenn, Jéru, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Laminopathies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973242/
https://ncbi.nlm.nih.gov/pubmed/29578370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2018.1456217
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados