LMNA Mutations Induce a Non-Inflammatory Fibrosis and a Brown Fat-Like Dystrophy of Enlarged Cervical Adipose Tissue

Some LMNA mutations responsible for insulin-resistant lipodystrophic syndromes are associated with peripheral subcutaneous lipoatrophy and faciocervical fat accumulation. Their pathophysiologic characteristics are unknown. We compared histologic, immunohistologic, ultrastructural, and protein expres...

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Detalhes bibliográficos
Main Authors: Béréziat, Véronique, Cervera, Pascale, Le Dour, Caroline, Verpont, Marie-Christine, Dumont, Sylvie, Vantyghem, Marie-Christine, Capeau, Jacqueline, Vigouroux, Corinne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204020/
https://ncbi.nlm.nih.gov/pubmed/21945321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.049
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