An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor

Determinants and mechanisms of cell attachment and entry steer adeno-associated virus (AAV) in its utility as a gene therapy vector. Thus far, a systematic assessment of how diverse AAV serotypes engage their proteinaceous receptor AAVR (KIAA0319L) to establish transduction has been lacking, despite...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Dudek, Amanda M., Pillay, Sirika, Puschnik, Andreas S., Nagamine, Claude M., Cheng, Fang, Qiu, Jianming, Carette, Jan E., Vandenberghe, Luk H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972900/
https://ncbi.nlm.nih.gov/pubmed/29343568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02213-17
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