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Adeno-Associated Virus Type 12 (AAV12): a Novel AAV Serotype with Sialic Acid- and Heparan Sulfate Proteoglycan-Independent Transduction Activity

Recombinant adeno-associated virus (rAAV) is a promising vector for gene therapy. Recent isolations of novel AAV serotypes have led to significant advances by broadening the tropism and increasing the efficiency of gene transfer to the desired target cell. However, a major concern that remains is th...

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Autori principali: Schmidt, Michael, Voutetakis, Antonis, Afione, Sandra, Zheng, Changyu, Mandikian, Danielle, Chiorini, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224443/
https://ncbi.nlm.nih.gov/pubmed/18045941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02012-07
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