Long-term transduction of miniature pig parotid glands using serotype 2 adeno-associated viral vectors

BACKGROUND: Previously, using an adenoviral vector, we showed that miniature pigs could provide a valuable and affordable large animal model for pre-clinical gene therapy studies to correct parotid gland radiation damage. However, adenoviral vectors lead to short-term transgene expression and, ideal...

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Detalhes bibliográficos
Publicado no:J Gene Med
Main Authors: Hai, Bo, Yan, Xing, Voutetakis, Antonis, Zheng, Changyu, Cotrim, Ana P., Shan, Zhaochen, Ding, Gang, Zhang, Chunmei, Xu, Junji, Goldsmith, Corinne M., Afione, Sandra, Chiorini, John A., Baum, Bruce J., Wang, Songlin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258189/
https://ncbi.nlm.nih.gov/pubmed/19326368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1319
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