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Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands

OBJECTIVES: Salivary glands are useful target organs for local and systemic gene therapeutics. For such applications, the regulation of transgene expression is important. Previous studies by us in murine submandibular glands showed that a rapamycin transcriptional regulation system in a single serot...

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Detalhes bibliográficos
Main Authors: Zheng, Changyu, Voutetakis, Antonis, Metzger, Mark, Wainer, Sandra, Cotrim, Ana P., Eckhaus, Michael A., Rivera, Victor M., Clackson, Tim, Chiorini, John A., Donahue, Robert E., Dunbar, Cynthia E., Baum, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852890/
https://ncbi.nlm.nih.gov/pubmed/20374510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-0825.2009.01631.x
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