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Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer

The apolipoprotein mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) proteins are a family of seven cytidine deaminases (A3A, A3B, A3C, A3D, A3F, A3G and A3H) that restrict certain viral infections. These innate defence factors are best known for their ability to restrict the replicatio...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Wang, Yaqiong, Schmitt, Kimberly, Guo, Kejun, Santiago, Mario L., Stephens, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972328/
https://ncbi.nlm.nih.gov/pubmed/26489798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000320
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