High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

APOBEC3G (A3G) and related deoxycytidine deaminases are potent intrinsic antiretroviral factors. A3G is expressed either as an enzymatically active low-molecular-mass (LMM) form or as an enzymatically inactive high-molecular-mass (HMM) ribonucleoprotein complex. Resting CD4 T cells exclusively expre...

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Detalles Bibliográficos
Autores principales: Chiu, Ya-Lin, Witkowska, H. Ewa, Hall, Steven C., Santiago, Mario, Soros, Vanessa B., Esnault, Cécile, Heidmann, Thierry, Greene, Warner C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592537/
https://ncbi.nlm.nih.gov/pubmed/17030807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604524103
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