Ift25 Is Not a Cystic Kidney Disease Gene but Is Required for Early Steps of Kidney Development

Eukaryotic cilia are assembled by intraflagellar transport (IFT) where large protein complexes called IFT particles move ciliary components from the cell body to the cilium. Defects in most IFT particle proteins disrupt ciliary assembly and cause mid gestational lethality in the mouse. IFT25 and IFT...

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Udgivet i:Mech Dev
Main Authors: Desai, Paurav B., San Agustin, Jovenal T., Stuck, Michael W., Jonassen, Julie A., Bates, Carlton M., Pazour, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972074/
https://ncbi.nlm.nih.gov/pubmed/29626631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2018.04.001
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