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Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease

Primary cilia project from the surface of most vertebrate cells and are thought to be sensory organelles. Defects in primary cilia lead to cystic kidney disease, although the ciliary mechanisms that promote and maintain normal renal function remain incompletely understood. In this work, we generated...

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Detalhes bibliográficos
Main Authors: Jonassen, Julie A., San Agustin, Jovenal, Follit, John A., Pazour, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575779/
https://ncbi.nlm.nih.gov/pubmed/18981227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808137
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