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Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
Primary cilia project from the surface of most vertebrate cells and are thought to be sensory organelles. Defects in primary cilia lead to cystic kidney disease, although the ciliary mechanisms that promote and maintain normal renal function remain incompletely understood. In this work, we generated...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575779/ https://ncbi.nlm.nih.gov/pubmed/18981227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200808137 |
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