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Disruption of IFT Complex A Causes Cystic Kidneys without Mitotic Spindle Misorientation
Intraflagellar transport (IFT) complexes A and B build and maintain primary cilia. In the mouse, kidney-specific or hypomorphic mutant alleles of IFT complex B genes cause polycystic kidneys, but the influence of IFT complex A proteins on renal development is not well understood. In the present stud...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312512/ https://ncbi.nlm.nih.gov/pubmed/22282595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011080829 |
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