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IFT27 Links the BBSome to IFT for Maintenance of the Ciliary Signaling Compartment
Vertebrate hedgehog signaling is coordinated by the differential localization of the receptors patched-1 and smoothened in the primary cilium. Cilia assembly is mediated by intraflagellar transport (IFT) and cilia defects disrupt hedgehog signaling, causing many structural birth defects. We generate...
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| 發表在: | Dev Cell |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254547/ https://ncbi.nlm.nih.gov/pubmed/25446516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.09.011 |
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