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Ift25 Is Not a Cystic Kidney Disease Gene but Is Required for Early Steps of Kidney Development

Eukaryotic cilia are assembled by intraflagellar transport (IFT) where large protein complexes called IFT particles move ciliary components from the cell body to the cilium. Defects in most IFT particle proteins disrupt ciliary assembly and cause mid gestational lethality in the mouse. IFT25 and IFT...

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Détails bibliographiques
Publié dans:Mech Dev
Auteurs principaux: Desai, Paurav B., San Agustin, Jovenal T., Stuck, Michael W., Jonassen, Julie A., Bates, Carlton M., Pazour, Gregory J.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972074/
https://ncbi.nlm.nih.gov/pubmed/29626631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2018.04.001
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