Landscape of Microsatellite Instability Across 39 Cancer Types

PURPOSE: Microsatellite instability (MSI) is a pattern of hypermutation that occurs at genomic microsatellites and is caused by defects in the mismatch repair system. Mismatch repair deficiency that leads to MSI has been well described in several types of human cancer, most frequently in colorectal,...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Bonneville, Russell, Krook, Melanie A., Kautto, Esko A., Miya, Jharna, Wing, Michele R., Chen, Hui-Zi, Reeser, Julie W., Yu, Lianbo, Roychowdhury, Sameek
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972025/
https://ncbi.nlm.nih.gov/pubmed/29850653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00073
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