Landscape of Microsatellite Instability Across 39 Cancer Types

PURPOSE: Microsatellite instability (MSI) is a pattern of hypermutation that occurs at genomic microsatellites and is caused by defects in the mismatch repair system. Mismatch repair deficiency that leads to MSI has been well described in several types of human cancer, most frequently in colorectal,...

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Dettagli Bibliografici
Pubblicato in:JCO Precis Oncol
Autori principali: Bonneville, Russell, Krook, Melanie A., Kautto, Esko A., Miya, Jharna, Wing, Michele R., Chen, Hui-Zi, Reeser, Julie W., Yu, Lianbo, Roychowdhury, Sameek
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2017
Soggetti:
Original Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972025/
https://ncbi.nlm.nih.gov/pubmed/29850653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00073
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