Detection of microsatellite instability biomarkers via next-generation sequencing

A high level of microsatellite instability (MSI-H+) is an emerging predictive and prognostic biomarker for immunotherapy response in cancer. Recently, MSI-H+ has been detected withinin a variety of cancer types, in addition to the classical cancers associated with Lynch Syndrome. Clinical testing fo...

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Опубликовано в: :Methods Mol Biol
Главные авторы: Bonneville, Russell, Krook, Melanie A., Chen, Hui-Zi, Smith, Amy, Samorodnitsky, Eric, Wing, Michele R., Reeser, Julie W., Roychowdhury, Sameek
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010320/
https://ncbi.nlm.nih.gov/pubmed/31502149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9773-2_5
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