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Laminin-deficient Muscular Dystrophy: Molecular Pathogenesis and Structural Repair Strategies

Laminins are large heterotrimers composed of the α, β and γ subunits with distinct tissue-specific and developmentally regulated expression patterns. The laminin-α2 subunit, encoded by the LAMA2 gene, is mainly expressed in skeletal muscle, Schwann cells of the peripheral nerve and astrocytes and pe...

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: Yurchenco, Peter D., McKee, Karen K., Reinhard, Judith R., Rüegg, Markus A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971131/
https://ncbi.nlm.nih.gov/pubmed/29191403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2017.11.009
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