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Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice
LAMA2-related muscular dystrophy (LAMA2 MD or MDC1A) is the most frequent form of early-onset, fatal congenital muscular dystrophies. It is caused by mutations in LAMA2, the gene encoding laminin-α2, the long arm of the heterotrimeric (α2, β1, and γ1) basement membrane protein laminin-211 (Lm-211)....
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| Izdano u: | Sci Transl Med |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5744687/ https://ncbi.nlm.nih.gov/pubmed/28659438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal4649 |
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