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RhoA Inactivation by p190RhoGAP Regulates Cell Spreading and Migration by Promoting Membrane Protrusion and Polarity

The binding of extracellular matrix proteins to integrins triggers rearrangements in the actin cytoskeleton by regulating the Rho family of small GTPases. The signaling events that mediate changes in the activity of Rho proteins in response to the extracellular matrix remain largely unknown. We have...

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Detalles Bibliográficos
Main Authors: Arthur, William T., Burridge, Keith
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC59706/
https://ncbi.nlm.nih.gov/pubmed/11553710
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