ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial–mesenchymal transition and enhancing DNA damage

The ataxia-telangiectasia-mutated (ATM) and rad3-related (ATR) checkpoint pathway plays an essential role in modulating cellular responses to replication stress and DNA damage to maintain genomic stability. In various tumors, cancer cells have increased dependence on ATR signaling for survival, maki...

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Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Song, Na, Jing, Wei, Li, Ce, Bai, Ming, Cheng, Yu, Li, Heming, Hou, Kezuo, Li, Yanrong, Wang, Kai, Li, Zhi, Liu, Yunpeng, Qu, Xiujuan, Che, Xiaofang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2018
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969561/
https://ncbi.nlm.nih.gov/pubmed/29157079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1404206
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