ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial–mesenchymal transition and enhancing DNA damage

The ataxia-telangiectasia-mutated (ATM) and rad3-related (ATR) checkpoint pathway plays an essential role in modulating cellular responses to replication stress and DNA damage to maintain genomic stability. In various tumors, cancer cells have increased dependence on ATR signaling for survival, maki...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Cycle
Päätekijät: Song, Na, Jing, Wei, Li, Ce, Bai, Ming, Cheng, Yu, Li, Heming, Hou, Kezuo, Li, Yanrong, Wang, Kai, Li, Zhi, Liu, Yunpeng, Qu, Xiujuan, Che, Xiaofang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2018
Aiheet:
Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969561/
https://ncbi.nlm.nih.gov/pubmed/29157079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1404206
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia