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Interplay between p53 and Ink4c in spermatogenesis and fertility

The tumor suppressor p53, and the cyclin-dependent kinase inhibitor Ink4c, have been both implicated in spermatogenesis control. Both p53-/- and Ink4c-/- single knockout male mice are fertile, despite testicular hypertrophy, Leydig cell differentiation defect, and increased sperm count in Ink4c-/- m...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Zalzali, Hassan, Rabeh, Wissam, Najjar, Omar, Abi Ammar, Rami, Harajly, Mohamad, Saab, Raya
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969541/
https://ncbi.nlm.nih.gov/pubmed/29334315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1421874
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