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Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility
A key player in the intracellular trafficking network is cytoplasmic dynein, a protein complex that transports molecular cargo along microtubules. Vertebrate dynein’s movement becomes strikingly enhanced upon interacting with dynactin and a cargo-adapter, such as BicaudalD2. However, the mechanisms...
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| Veröffentlicht in: | Nat Struct Mol Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5969528/ https://ncbi.nlm.nih.gov/pubmed/29416113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0027-7 |
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