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The Suppression of Medium Acidosis Improves the Maintenance and Differentiation of Human Pluripotent Stem Cells at High Density in Defined Cell Culture Medium

Cell density has profound impacts on the cell culture practices of human pluripotent stem cells. The regulation of cell growth, cell death, pluripotency and differentiation converge at high density, but it is largely unknown how different regulatory mechanisms act at this stage. We use a chemically...

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Detalles Bibliográficos
Publicado en:Int J Biol Sci
Main Authors: Liu, Weiwei, Ren, Zhili, Lu, Kai, Song, Chengcheng, Cheung, Edwin Chong Wing, Zhou, Zhou, Chen, Guokai
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968841/
https://ncbi.nlm.nih.gov/pubmed/29805300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.24681
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